If you have a sulfur sensitivity, glutathione can be problematic. Glutathione is primarily made up of sulfur, which can cause issues for those with a sulfur sensitivity. While Glutathione is an Sulfur metabolism under stress: Oxidized glutathione inhibits methionine biosynthesis by destabilizing the enzyme cystathionine synthase Hacham 2025 Journal of Integrative Plant Biology Wiley Online Library Biotechnological tools for reducing the use of sulfur dioxide in white grape must and preventing enzymatic browning: glutathione; inactivated dry yeasts rich in glutathione; and bioprotection with Metschnikowia pulcherrima European Food Glutathione S transferase Wikipedia
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glutathione sulfur sensitivity Figure 1 from Glutathione redox cycle protects cultured endothelial cells against lysis by extracellularly generated hydrogen peroxide