Acetaminophen Use During Pregnancy and Autism Risk Since everyone is talking about Tylenol let's actually talk about Tylenol. No, it doesn't cause autism But here's what it can do: Deplete glutathione: one of your body's most PDF] Evidence that Increased Acetaminophen use in Genetically Vulnerable Children Appears to be a Major Cause of the Epidemics of Autism, Attention Deficit with Hyperactivity, and Asthma Semantic Scholar Tylenol can lower the body's key antioxidant, glutathione, though this isn't seen on routine labs. But mechanistic data clinical proof, so we still need good trials. The Tylenolautism link isn't clear.