The Pentose Phosphate Pathway in Parasitic Trypanosomatids: Trends in Parasitology Pentose phosphate pathway: phases, reactions, & metabolic roles Do we need to memorize the structures of the pentose phosphate pathway molecules (e.g. pics 1 and 2) if we want a 130+? Also do we need to know the glutathione part Glucose metabolism begins with its transport into cells via GLUT transporters, where it is phosphorylated to glucose 6 phosphate (Glucose 6 P). This molecule can enter various pathways, including the pentose phosphate pathway or hexosamine biosynthesis.