Mycotoxin induced depletion of intracellular glutathione and altered cytokine production in the human alveolar epithelial cell line A549 ScienceDirect Identification of cytotoxic, glutathione reactive moieties inducing accumulation of reactive oxygen species via glutathione depletion ScienceDirect Mycotoxins are toxic. But they are only one of many stressors affecting the extracellular matrix. Ochratoxin, aflatoxins, and trichothecenes increase oxidative stress, deplete glutathione, disrupt mitochondria, and activate inflammatory signaling. That Mycotoxin Properties and Metabolism: Part 2 Great Plains Laboratory