For 20 years, it seemed "obvious" that NSAIDs blunt training adaptation. Trappe 2002 showed ibuprofen suppressed muscle protein synthesis 24 hours after exercise. Mikkelsen 2009 showed a local NSAID infusion blocked satellite Psychopharmacology Debates: Tylenol or NSAIDs? Nonsteroidal Anti inflammatory Drugs, Acetaminophen, and COX 2 Inhibitors Anesthesia Key Psychopharmacology Debates: Tylenol or NSAIDs?
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