In RBCs, NADPH are produced exclusively via HMP shunt by the action of G6PD and are responsible to maintain membrane integrity preventing premature destruction. That is why G6PD deficient RBCs are Frontiers The global role of G6PD in infection and immunity G6PD deficiency and malaria Medications and Glucose 6 Phosphate Dehydrogenase : Drug Safety
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role of glutathione in g6pd deficiency Understanding and Managing Glucose-6-Phosphate Dehydrogenase Deficiency