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foxo4-dri peptide mechanism of action Frontiers
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foxo4-dri peptide mechanism of action Frontiers
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p53 regulated senescence mechanism and role of its modulators in age related disorders ScienceDirect The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv
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foxo4-dri peptide mechanism of action Frontiers
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