Glutathione for the skin Paula's Choice Glutathione is such an important antioxidant in human physiology, meaning it acts to combat oxidative stress. Strategies for increasing glutathione include: Consume sulfur rich foods like cruciferous vegetables Ensure you get What is glutathione and why must we protect patient access to it? Glutathione is a natural antioxidant your body makes, and it can influence melanin production which is why its sometimes marketed for skin brightening., Oral supplements are mostly broken down in