Pigmented Lesions of the Oral Mucosa: Clinical Presentation, Histology, and Recommendations for Management American Journal of Clinical Dermatology Springer Nature Link Melanotic Macule Lip TikTok This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in