Pigmented Lesions of the Oral Mucosa Pocket Dentistry Labial or Oral Melanotic Macule Benign, asymptomatic, and often underdiagnosed. Swipe to learn how to recognize, diagnose, and manage this simple yet important lesion! #thebasicdentist #rguhs #kuhs #tnmgrmu #OralPathology #MelanoticMacule #DentalFacts Pigmented Lesions of the Oral Cavity Oral and Maxillofacial Surgery Clinics Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule.