Here's exactly what you need to know about those velvety dark patches in body folds. . . . [ Acanthosis nigricans, elbows, knees, armpits darkness, how to get rid of dark skin, Glutathione is often called the master antioxidant But it's actually regulated by melatonin (PMID: 20868358) Melatonin has been seen to have 10x the antioxidant capacity than glutathione Besides sleep, melatonin also regulates Glutathione Skin Whitening Does It Really Work? Glutathione and Brain Health: What It Is, Sources, And Benefits