Oral Liposomal Copper GHK Liposomal GHK Cu Supplement Defy GHK Cu (glycyl L histidyl L lysine) is a naturally occurring copper binding peptide found in human plasma. As levels decline with age, so may its support of the biological processes involved in collagen production, skin Defy GHK Cu (glycyl L histidyl L lysine) is a naturally occurring copper binding peptide found in human plasma. As levels decline with age, so may its support of the biological processes involved in collagen production, skin Does GHK Cu Really Work? 40 Years of Research Reviewed