EASL Clinical Practice Guidelines: Wilson's disease ScienceDirect What is the safe topical dosing, duration, and contraindications for the copperbinding peptide GHKCu for wound healing or antiaging? Is topical GlycylLhistidylLlysine copper (GHKCu) safe for adults, and what are the risks, contraindications, and considerations for systemic use, pregnancy, lactation, and children? What is Wilson disease? It's a rare condition where excess copper builds up in the body, affecting the function of the liver, brain, and other organs. Early signs and symptoms