What is the pipeline for future medications for obesity? International Journal of Obesity For an adult with type 2 diabetes mellitus who requires substantial weight loss, what are the recommended use, dosing, regulatory approval status, and contraindications of tirzepatide compared with cagrilintide, and what alternative PDF] Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 24 mg for weight management: a randomised, controlled, phase 1b trial. Semantic Scholar cagrisema #semaglutide #amylin #glp1 #obesity #dualincretins Yulia Lurye, MD