The distance between a compound demonstrating efficacy in preclinical research and that compound appearing in a physician's standard toolkit can span a generation. The mechanisms by which NAC addresses oxidative stress, glutamate Research on Antioxidant Role in Schizophrenia and Psychosis Points to Possible Therapeutic Value of Compound Found in Broccoli Brain & Behavior Research Foundation Early treatment response in first episode psychosis: a 7 T magnetic resonance spectroscopic study of glutathione and glutamate Molecular Psychiatry N Acetylcysteine effects on glutathione and glutamate in schizophrenia: A preliminary MRS study ScienceDirect
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