Could a vitamin deficiency cause 'double jointedness' and hypermobile Ehlers Danlos syndrome? Cellular and Molecular Mechanisms in the Pathogenesis of Classical, Vascular, and Hypermobile EhlersDanlos Syndromes Biological insights in the pathogenesis of hypermobile Ehlers Danlos syndrome from proteome profiling of patients' dermal myofibroblasts ScienceDirect The Ehlers Danlos syndromes (EDS) are a group of heritable connective tissue disorders that vary in the ways they affect the body and in their genetic causes. Variants in the genes