Understanding the Legal Risks of BPC 157 and Other Unapproved Peptides Holt Law BPC 157 has a decades long safety record with zero deaths or hospitalizations. Yet, it's unapproved because the FDA process is too expensive and the business model doesn't allow for profit. Approved drugs with BPC 157 & The Gut Brain Axis: A Practitioner's Definitive Review of the Evidence BPC 157: Experimental Peptide Creates Risk for Athletes