The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv Quick guide: reconstituting peptides the right way Sanitize vial & prep materials Add bacteriostatic water slowly (aim at the side) Gently swirl, don't shake Proper handling helps maintain FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology
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