Are E Cigarettes a Safe Alternative to Smoking? Using Airway Cell Cultures to Assess Early Indicators of COPD Progression Inquiries Journal E cigarette use tied to increased COPD, asthma risk MDedge A new study published in Nicotine & Tobacco Research found that those using e cigarettes alone were more than twice as likely to develop COPD than people who didn't use any tobacco products, E Cigarette use linked to COPD and hypertension in large study