Conceptual framework how chronic kidney disease, inflammation, and Download Scientific Diagram Full article: Glutathione metabolism rewiring protects renal tubule cells against cisplatin induced apoptosis and ferroptosis WhyScience #Day33: Genome wide studies have uncovered >1,000 loci linked to kidney function, but pinpointing causal genes remains a hurdle. In our new @SciTransMed paper, we integrated human multi omics and mouse models to Glutathione deficiency alters the vitamin D metabolizing enzymes CYP27B1 and CYP24A1 in human renal proximal tubule epithelial cells and kidney of HFD fed mice ScienceDirect
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glutathione kidney disease X-ray structure of glutathione S-transferase from the malarial parasite Plasmodium falciparum