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Glutathione Homeostasis and Functions: Potential Targets for Medical Interventions Lushchak 2012 Journal of Amino Acids Wiley Online Library Molecular Vision: De Donatis, Mol Vis 2010; 16:1025 1033. Figure 1 Hepatic Glutathione Synthesis: The Liver's Antioxidant Powerhouse Glutathione (GSH) is the most abundant intracellular antioxidantand the liver is its primary production site. Through a tightly regulated, ATP dependent pathway, hepatocytes Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation eLife
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