Tylenol (acetaminophen) does not cause autism. The FDA, in its statement that there may be an association, confirmed that "a causal relationship has not been established, and studies of millions of children Tylenol, Autism, and Leucovorin: What Parents Need to Know. Is Tylenol Safe During Pregnancy? Understanding Risk Factors Seeking Health Evaluating the Role of Susceptibility Inducing Cofactors and of Acetaminophen in the Etiology of Autism Spectrum Disorder